Pattern recognition analysis of anterior cingulate cortex blood flow to classify depression polarity†

نویسندگان

  • J. R. C. Almeida
  • J. Mourao-Miranda
  • H. J. Aizenstein
  • A. Versace
  • F. A. Kozel
  • H. Lu
  • A. Marquand
  • E. J. LaBarbara
  • M. Brammer
  • M. Trivedi
  • D. J. Kupfer
  • M. L. Phillips
چکیده

Differentiating bipolar from recurrent unipolar depression is a major clinical challenge. In 18 healthy females and 36 females in a depressive episode--18 with bipolar disorder type I, 18 with recurrent unipolar depression--we applied pattern recognition analysis using subdivisions of anterior cingulate cortex (ACC) blood flow at rest, measured with arterial spin labelling. Subgenual ACC blood flow classified unipolar v. bipolar depression with 81% accuracy (83% sensitivity, 78% specificity).

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عنوان ژورنال:

دوره 203  شماره 

صفحات  -

تاریخ انتشار 2013